MAPK6 Antibodies, cDNA Clones Research Reagents

MAPK6 (Mitogen-Activated Protein Kinase 6, also known as ERK3; PRKM6; p97MAPK; HsT17250), located on 15q21.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The gene produces an 82681 Da protein composed of 721 amino acids. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is most closely related to mitogen-activated protein kinases (MAP kinases). Diseases such as Pulmonary Immaturity and Breast Mucoepidermoid Carcinoma are associated with MAPK6. The related pathways of MAPK6 include Signaling by GPCR and VEGF Signaling.

MAPK6 Antibody (1)

    MAPK6 cDNA Clone (30)

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    MAPK6 Background

    MAPK6 (Mitogen-Activated Protein Kinase 6) is a Protein Coding gene. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is most closely related to mitogen-activated protein kinases (MAP kinases). MAPK signaling is a critical pathway in many biological processes. MAPK6 is most highly expressed in liver cancer samples. A divergent lncRNA (long non-coding RNA) of MAPK6, termed lncMAPK6 here, is also overexpressed along with liver tumorigenesis. It was the most highly expressed MAPK component in liver cancer and liver TICs and lncMAPK6 participated in the transcriptional regulation of MAPK6in cis. MAPK6 is widely expressed in the testis, brain, and other tissues. Diseases associated with MAPK6 include Pulmonary Immaturity and Breast Mucoepidermoid Carcinoma.

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