Lymphotoxin Beta Proteins, cDNA Clones Research Reagents

LTB (Lymphotoxin Beta, also known as p33; TNFC; TNFSF3; TNLG1C), located on 6p21.33, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. The gene produces a 25390 Da protein composed of 244 amino acids. Lymphotoxin beta is a type II membrane protein of the TNF family. Diseases such as Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency are associated with LTB. The related pathways of LTB include NF-KappaB Family Pathway and LT-BetaR Pathway.

Lymphotoxin Beta Protein (1)

    Lymphotoxin Beta cDNA Clone (65)

    NM_002341.1
    NM_009588.1
    NM_008518.2
    NM_001047150.1
    NM_001033510.1

    Lymphotoxin Beta Lysate (1)

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      Lymphotoxin Beta Background

      LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.

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