LILRA5 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All LILRA5 reagents are produced in house and quality controlled, including 7 LILRA5 Antibody, 1 LILRA5 ELISA, 39 LILRA5 Gene, 4 LILRA5 Lysate, 6 LILRA5 Protein, 2 LILRA5 qPCR. All LILRA5 reagents are ready to use.

LILRA5 Protein (6)

    LILRA5 Antibody (7)

      LILRA5 ELISA Kit & Match Antibody ELISA Pair Set (1)

      LILRA5 cDNA Clone (39)

      NM_021250.2
      NM_001081239.2
      NM_001076793.1

      LILRA5 qPCR Primer (2)

      LILRA5 Lysate (4)

        LILRA5 Background

        LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

        LILRA5 References

        • Wende H, et al. (2000) Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster. Immunogenetics. 51(8-9):703-13.
        • Jones DC, et al. (2009) Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes. Eur J Immunol. 39(11):3195-206.
        • Mosbruger TL, et al. (2010) Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. J Infect Dis. 201(9):1371-80.

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