KLRC3 Antibodies, cDNA Clones Research Reagents

KLRC3 (Killer Cell Lectin Like Receptor C3, also known as NKG2E; NKG2-E), located on 12p13.2, is a Protein Coding gene. The gene produces a 27100 Da protein composed of 240 amino acids. KLRC3 is a member of the NKG2 group which is expressed primarily in natural killer (NK) cells. KLRC3 gene expression is linked to glioblastoma aggressiveness and could be a new potential therapeutic target to attenuate glioblastoma. Diseases such as Monkeypox are associated with KLRC3. The related pathways of KLRC3 include the Immune response Role of DAP12 receptors in NK cells and Allograft rejection.

KLRC3 Antibody (1)

    KLRC3 cDNA Clone (14)

    NM_002261.2

    In expression vector

    AF395616

    KLRC3 Background

    KLRC3 (Killer Cell Lectin Like Receptor C3) is a Protein Coding gene. KLRC3 is a member of the NKG2 group which is expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. Expression of KLRC3 in type 1 diabetes mellitus (T1DM) might play a role in the pathogenesis of T1DM and could be a predictor of its severity.KLRC3 silencing decreased self-renewal capacity, invasion, proliferation, radioresistance, and tumourigenicity of U87-MG glioblastoma cell line.KLRC3 gene expression is linked to glioblastoma aggressiveness and could be a new potential therapeutic target to attenuate glioblastoma.

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