Kallikrein 13 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Kallikrein 13 reagents are produced in house and quality controlled, including 6 Kallikrein 13 Antibody, 2 Kallikrein 13 ELISA, 26 Kallikrein 13 Gene, 1 Kallikrein 13 Lysate, 1 Kallikrein 13 Protein, 3 Kallikrein 13 qPCR. All Kallikrein 13 reagents are ready to use.

Kallikrein 13 Protein (1)

    Kallikrein 13 Antibody (6)

      Kallikrein 13 ELISA Kit & Match Antibody ELISA Pair Set (2)

      Kallikrein 13 cDNA Clone (26)


      Kallikrein 13 Lysate (1)

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        Kallikrein 13 Background

        Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.

        Kallikrein 13 References

        • Yousef G.M., et al.,(2000), Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues. J. Biol. Chem. 275:11891-11898.
        • Komatsu N., et al., (2003), Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages.J. Invest. Dermatol. 121:542-549.
        • Andres A.M., et al.,(2007), Understanding the accuracy of statistical haplotype inference with sequence data of known phase.Genet. Epidemiol. 31:659-671.

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