Block Beads with BSA in Immunoprecipitation (IP)

How can I block Immunomagnetic beads Protein A, Protein G and protein L with BSA?

Blocking with BSA works best on a hydrophobic surface, where surface adsorption keeps the blocker in position. Immunomagnetic beads Protein A, Protein G and protein L have a hydrophilic surface. Therefore, BSA blocking may not be very successful, as surface adsorption is not promoted between the hydrophilic bead surface and the hydrophobic BSA.
Instead, reduce non-specific binding by performing more stringent washing and by adding Tween-20 detergent (concentrations of 0.01–0.1% ) to the washing buffer.