Interferon alpha-B Proteins, Antibodies, cDNA Clones Research Reagents

IFNA8 (Interferon Alpha 8, also known as IFN-alphaB), located on 9p21.3, is a Protein Coding gene. The gene produces a 21989 Da protein composed of 189 amino acids. IFNA8 belongs to the alpha/beta interferon family. Produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Diseases such as St. Louis Encephalitis and Common Wart are associated with IFNA8. The related pathways of IFNA8 include all-trans-retinoic Acid Mediated Apoptosis and Tuberculosis.

Interferon alpha-B Protein (4)

    Interferon alpha-B Antibody (4)

      Interferon alpha-B cDNA Clone (26)

      NM_002170.3
      XM_001107458.2

      Interferon alpha-B qPCR Primer (1)

      Interferon alpha-B Lysate (4)

        Interferon alpha-B Background

        Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infections by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha has antiviral activities.

        Interferon alpha-B References

        • Henco K. et al., 1985, J Mol Biol. 185 (2): 227-60.
        • Goeddel DV. et al., 1981, Nature. 290 (5801): 20-6.
        • Yelverton E. et al., 1981, Nucleic Acids Res. 9 (3): 731-41.
        • Kempaiah P. et al., 2012, Hum Genet. 131 (8): 1375-91.

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