Interferon alpha 10/IFNA10 Proteins, Antibodies, cDNA Clones Research Reagents

IFNA10 (Interferon Alpha 10, also known as IFN-alphaC), located on 9p21.3, is a Protein Coding gene. The gene produces a 21835 Da protein composed of 189 amino acids. This gene encodes a protein that belongs to the type I interferon family of proteins and is located in a cluster of alpha interferon genes on chromosome 9. Human IFN is divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons. The related pathways of IFNA10 include all-trans-retinoic Acid Mediated Apoptosis and Tuberculosis.

Interferon alpha 10/IFNA10 Protein (3)

    Interferon alpha 10/IFNA10 Antibody (1)

      Interferon alpha 10/IFNA10 cDNA Clone (13)

      NM_002171.1

      Interferon alpha 10/IFNA10 qPCR Primer (1)

      Interferon alpha 10/IFNA10 Lysate (2)

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        Interferon alpha 10/IFNA10 Background

        Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they increase the ability of uninfected host cells to resist new infection by the virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons.

        Interferon alpha 10/IFNA10 References

        • De Veer MJ, et al. (2001) Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol. 69 (6): 912-20.
        • Liu YJ. (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol. 23: 275-306.
        • Fensterl V, et al. (2009) Interferons and viral infections. Biofactors. 35 (1): 14-20.

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