IL-13 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All IL-13 reagents are produced in house and quality controlled, including 10 IL-13 Antibody, 2 IL-13 ELISA, 39 IL-13 Gene, 5 IL-13 Lysate, 5 IL-13 Protein, 3 IL-13 qPCR. All IL-13 reagents are ready to use.

IL-13 Protein (5)

    IL-13 Antibody (10)

      IL-13 ELISA Kit & Match Antibody ELISA Pair Set (2)

      IL-13 cDNA Clone (39)

      NM_002188.2
      NM_008355.2
      NM_053828.1

      IL-13 Lysate (5)

        More Product Popular With Customers

        IL-13 Background

        Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

        IL-13 References

        • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
        • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.