Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.
Tonsils are lumps of soft tissue and are part of the immune system. The tonsils are a pair of soft tissue masses located at the rear of the throat, and form the first station of defense againstAll ingested and inhales pollutants. The tonsils play a role in protecting the body from respiratory and gastrointestinal infections. Tonsils can become enlarged or inflamed. If they obstruct the airway or interfere with swallowing, or in patients with frequent recurrent tonsillitis, they may be required surgical removal. However, removal of the tonsils does not seem to increase susceptibility to infection. Tonsil cancer is a type of cancer that begins in the cells of your tonsils, Tonsil cancer often causes difficulty swallowing and a sensation that something is caught in your throat. Tonsil cancer is often diagnosed late in the disease, when cancer has spread to nearby areas, such as the tongue and the lymph nodes. The number one symptom of tonsil cancer is asymmetrical tonsils, having one tonsil larger than the other. Another symptom is a persistent sore throa. Early-stage tonsil cancer is often treated with radiation therapy. Induction chemotherapy can also be used to reduce the tonsil tumor. In advanced cancer, usually requires a combination of surgery, radiotherapy and chemotherapy.A variety of target molecules expressed on tonsil tissue is used for the clinical diagnosis of tonsil disease, tonsil tissue is commonly used in immunohistochemical detection. IHC is an important means to be widely used to detect tonsil disease.
Different species of tonsil slices as follows: