Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.
The stomach is a muscular organ located on the left side of the upper abdomen. It is a muscular, hollow, dilated part of the digestive system which functions as an important organ of the digestive tract in many animals. The stomach secretes acid and enzymes that digest food, through smooth muscular contractions before sending partially digested food (chyme) to the small intestines. Stomach cancer, or gastric cancer, is a relatively uncommon type of cancer. It is the third most common cause of cancer-related death in the world There are different types of stomach cancer. 95% develop in the cells of the stomach lining and are known as adenocarcinoma of the stomach. Stomach cancer tumor markers are substances found in the blood of patients and can be used to aid management of the condition. Tumor markers such as CEA and CA 19-9: Elevated CEA in 45-50% of cases; elevated CA 19-9 in about 20% of cases in stomach cancer.
Different species of stomach slices as follows: