Immunohistochemistry (IHC) Antibody-Pancreas Tissue

Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.

The pancreas is a long flattened gland located deep in the belly (abdomen). Part of the pancreas is sandwiched between the stomach and the spine. The other part is nestled in the curve of the duodenum. The pancreas is a glands organs in the digestive system and the endocrine system. In humans, it is located behind the stomach. It secretes several important hormones, including insulin, glucagon, somatostatin and pancreatic polypeptide. The pancreas is also a digestive organs that secretes digestive enzymes to help digestion and absorption of nutrients. In the small intestine, these enzymes help to further break down carbohydrates, proteins and lipids. A variety of target molecules expressed on pancreas tissue is used for the clinical diagnosis of pancreas disease, pancreas tissue is commonly used in immunohistochemical detection. IHC is an important means to be widely used to detect pancreas disease.

Different species of pancreas slices as follows

Human

CLPS: 13631-RP02

Immunochemical staining of human CLPS in human pancreas with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic acinus.
CPA1: 10504-RP02

Immunochemical staining of human CPA1 in human pancreas with rabbit polyclonal antibody (0.2 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic acinus.
IGFBP7: 13100-RP02

Immunochemical staining of human IGFBP7 in human pancreas with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic islet.
SPINK4: 11669-RP02

Immunochemical staining of human SPINK4 in human pancreas with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
INSR: 11081-RP02

Immunochemical staining of human INSR in human pancreas with rabbit polyclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections).

Mouse

mCPA2: 50778-R133

Immunochemical staining of mouse CPA2 in mouse pancreas with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
mFSTL1: 51127-T56

Immunochemical staining of mouse FSTL1 in mouse pancreas with rabbit polyclonal antibody (0.3 µg/mL, formalin-fixed paraffin embedded sections).
mGRN: 50396-RP02

Immunochemical staining of mouse GRN in mouse pancreas with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).