Immunohistochemistry in Ovarian Cancer

Immunohistochemical techniques is a methodology which based on antigen-antibody immunological response to its theoretical foundation. It plays an important role in basic and clinical medical research in the field of biology, especially in the diagnosis of diseases of the tumors, differential diagnosis and pathogenesis research provides a powerful tool. With the development of new technologies, hundreds of kinds of antibodies used in various areas of clinical research, the majority of these antibodies play an important supporting role in the diagnosis of difficult cases. It has important implications for the patient's prognosis and guide treatment.

A marker molecule called CA-125 is useful in differential diagnosis of ovarian cancer . HE4 is another marker for ovarian cancer testing, though it has not been extensively used. Other tumor markers for ovarian cancer include CA19-9, CA72-4, CA15-3, haptoglobin-alpha, immunosuppressive acidic protein, OVX1, lysophosphatidic acid, and fibroblast growth factor 23.

Slices of ovarian cancer as follows:

B2M: 11976-R209

Immunochemical staining of human B2M in human ovarian cancer with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
CCNE1: 10902-MM11

Immunochemical staining of human CCNE1 in human ovarian cancer with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). The image showing nucleus staining of cells.
CLU: 11297-R210

Immunochemical staining of human CLU in human ovarian cancer with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
EGFR: 10001-T24

Immunochemical staining of human EGFR in human ovarian cancer with rabbit polyclonal antibody (1 µg/mL,formalin-fixed paraffin embedded sections).
MUC1: 12123-T24

Immunochemical staining of human MUC1 in human ovarian cancer with rabbit polyclonal antibody (0.2 µg/mL,formalin-fixed paraffin embedded sections).