Immunohistochemistry (IHC) Antibody-Esophagus Tissue

Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.

The esophagus is the hollow tube that leads from the throat to the stomach. The esophagus is about 8 inches long, The esophagus is behind the windpipe (trachea) and heart, and in front of the spine. The wall of the esophagus from the lumen outwards consists of mucosa, sub-mucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. The esophagus seems to have only one important function in the body - to carry food, liquids, and saliva from the mouth to the stomach. A variety of target molecules expressed on esophagus tissue is used for the clinical diagnosis of esophagus disease, esophagus tissue is commonly used in immunohistochemical detection. IHC is an important means to be widely used to detect esophagus disease.

Different species of esophagus slices as follows

Human

CD44: 12211-MM01

Immunochemical staining of human CD44 in human esophagus with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). The image showing membrane staining of squamous epithelium cell.
CD147: 10186-MM05

Immunochemical staining of human CD147 in human esophagus with mouse monoclonal antibody (10 µg/mL, formalin-fixed paraffin embedded sections). The image showing membrane staining of squamous epithelium cell.
CRABP2: 11203-MM01

Immunochemical staining of human CRABP2 in human esophagus with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections).
DSC2: 10809-RP02

Immunochemical staining of human DSC2 in human esophagus with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of the squamous epithelium.
IL1F9: 10124-R013

Immunochemical staining of human IL1F9 in human esophagus with rabbit monoclonal antibody (0.05 µg/mL, formalin-fixed paraffin embedded sections).

Rat

ratACE2: 80031-R039

Immunochemical staining of rat ACE2 in rat esophagus with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).