HDAC2 Antibodies, cDNA Clones Research Reagents

HDAC2 (Histone Deacetylase 2, also known as HD2; RPD3; YAF1; KDAC2), located on 6q21, is a Protein Coding gene. The gene produces a 55364 Da protein composed of 488 amino acids. HDAC2 gene product belongs to the histone deacetylase family and is widely expressed in testis, endometrium, and other tissues. This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. It plays an important role in transcriptional regulation, cell cycle progression, and developmental events.

HDAC2 Antibody (1)

    HDAC2 cDNA Clone (2)

    NM_053447.1

    In cloning vector

    In lentiviral vector

    HDAC2 qPCR Primer (1)

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    HDAC2 Background

    HDAC2 (Histone Deacetylase 2) is a Protein Coding gene. HDAC2 gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3, and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternative splicing results in multiple transcript variants. HDAC2 is widely expressed in testis, endometrium, and other tissues. Diseases associated with HDAC2 include Pulmonary Disease, Chronic Obstructive, and Lung Disease.

    HDAC2 References

    • Hodge G, Jersmann H, Tran HB, et al. Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes. Respiratory Research. 2015;16:130.

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