HDAC1 Antibodies, cDNA Clones Research Reagents

All HDAC1 reagents are produced in house and quality controlled, including 2 HDAC1 Antibody, 30 HDAC1 Gene, 1 HDAC1 qPCR. All HDAC1 reagents are ready to use.

HDAC1 Antibody (2)

    HDAC1 cDNA Clone (30)

    HDAC1 qPCR Primer (1)

    HDAC1 Background

    Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

    HDAC1 References

    • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.

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