GBP2 Proteins, Antibodies, cDNA Clones Research Reagents

All GBP2 reagents are produced in house and quality controlled, including 2 GBP2 Antibody, 15 GBP2 Gene, 1 GBP2 Lysate, 1 GBP2 Protein, 1 GBP2 qPCR. All GBP2 reagents are ready to use.

GBP2 Protein (1)

    GBP2 Antibody (2)

      GBP2 cDNA Clone (15)

      GBP2 qPCR Primer (1)

      GBP2 Lysate (1)

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        GBP2 Background

        GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interferons that have antiviral effects and inhibit tumor cell proliferation.

        GBP2 References

        • Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
        • Wistow G, et al. (2002) Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. Mol Vis. 8:205-20.
        • Neun R, et al. (1996) GTPase properties of the interferon-induced human guanylate-binding protein 2. FEBS Lett. 390(1):69-72.

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