FGF12 Proteins, cDNA Clones Research Reagents

All FGF12 reagents are produced in house and quality controlled, including 60 FGF12 Gene, 1 FGF12 Protein, 2 FGF12 qPCR. All FGF12 reagents are ready to use.

FGF12 Protein (1)

    FGF12 cDNA Clone (60)

    FGF12 Background

    FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, FGF12 accumulated in the nucleus, but was not secreted. The specific function of FGF12 gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

    FGF12 References

    • Liu Y. et al., 1997, Cytogenet Cell Genet. 78 (1): 48-9.
    • Robertson NG. et al., 1995, Genomics. 23 (1): 42-50.
    • Smallwood PM. et al., 1996, Proc Natl Acad Sci. 93 (18): 9850-7.

    Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.