Cystatin F/CST7 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Cystatin F/CST7 reagents are produced in house and quality controlled, including 6 Cystatin F/CST7 Antibody, 1 Cystatin F/CST7 ELISA, 26 Cystatin F/CST7 Gene, 4 Cystatin F/CST7 Lysate, 4 Cystatin F/CST7 Protein, 2 Cystatin F/CST7 qPCR. All Cystatin F/CST7 reagents are ready to use.

Cystatin F/CST7 Protein (4)

    Cystatin F/CST7 Antibody (6)

      Cystatin F/CST7 ELISA Kit & Match Antibody ELISA Pair Set (1)

      Cystatin F/CST7 cDNA Clone (26)


      Cystatin F/CST7 Lysate (4)

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        Cystatin F/CST7 Background

        The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.

        Cystatin F/CST7 References

        • Halfon S., et al.,(1998), Leukocystatin, a new class II cystatin expressed selectively by hematopoietic cells. J. Biol. Chem. 273:16400-16408.
        • Ni J., et al., (1998), Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor.J. Biol. Chem. 273:24797-24804.
        • Morita M., et al.,(2000), Genomic construct and mapping of the gene for CMAP (leukocystatin/cystatin F, CST7) and identification of a proximal novel gene, BSCv (C20orf3).Genomics 67:87-91.

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