Carboxypeptidase A Proteins, Antibodies, cDNA Clones Research Reagents

All Carboxypeptidase A reagents are produced in house and quality controlled, including 7 Carboxypeptidase A Antibody, 52 Carboxypeptidase A Gene, 1 Carboxypeptidase A IP Kit, 2 Carboxypeptidase A Lysate, 2 Carboxypeptidase A Protein, 3 Carboxypeptidase A qPCR. All Carboxypeptidase A reagents are ready to use.

Carboxypeptidase A Protein (2)

    Carboxypeptidase A Antibody (7)

      Carboxypeptidase A cDNA Clone (52)


      Carboxypeptidase A Lysate (2)

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        Carboxypeptidase A Background

        Carboxypeptidase A1 (CPA1)is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated.

        Carboxypeptidase A References

        • Catasus, L. et al., 1992, Biochem. J. 287: 299-303.
        • Moulard, M. et al., 1990, FEBS. Lett. 261: 179-183.
        • Aloy, P. et al., 1998, Biol. Chem. 379: 149-155.

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