MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis, and cellular transformation. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. MYC is one of the most important oncogenes in cancer. MYC overexpression can be achieved through a variety of mechanisms, including gene duplications, chromosomal translocations, or somatic mutations leading to increased MYC stability. It is widely expressed in the gall bladder, esophagus, and other tissues. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement.