ATF1 Antibodies, cDNA Clones Research Reagents

All ATF1 reagents are produced in house and quality controlled, including 2 ATF1 Antibody, 18 ATF1 Gene. All ATF1 reagents are ready to use.

ATF1 Antibody (2)

    ATF1 cDNA Clone (18)

    NM_005171.4

    In cloning vector

    NM_001100895.1

    In cloning vector

    In lentiviral vector

    ATF1 Background

    Activating transcription factor 1 (ATF1) and RAS genes were significantly up-regulated in tumours of both primary and recurrent cervical cancer mouse model, and they can also be detected in the blood exosomes of the mouse model. Our results indicated that ATF1 and RAS could be potential candidate biomarkers for cervical cancer in early diagnosis. ATF1 and RAS genes were found significantly elevated in tumours of primary and recurrent cervical cancer mouse model, and they were also detected in the blood exosomes. Therefore, ATF1 and RAS could be used as a diagnostic marker for cervical cancer in the future. The transcription factor Atf1 is known to promote cell survival during various stress conditions in Schizosaccharomyces pombe by activating the expression of appropriate genes. It can also activate transcription of other important genes responsible for cell cycle progression. An Atf1-dependent increase in the expression of cell division promoting genes will oppose activation of checkpoints necessary to ensure repairs and cell survival during stress.

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