ANTXR2 Proteins, cDNA Clones Research Reagents

All ANTXR2 reagents are produced in house and quality controlled, including 39 ANTXR2 Gene, 3 ANTXR2 Lysate, 3 ANTXR2 Protein, 1 ANTXR2 qPCR. All ANTXR2 reagents are ready to use.

ANTXR2 Protein (3)

    ANTXR2 cDNA Clone (39)


    ANTXR2 qPCR Primer (1)

    ANTXR2 Lysate (3)

      ANTXR2 Background

      Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneous nodules, gingival hypertrophy and severe painful joint contracture. Anthrax toxin causes anthrax pathogenesis and expression levels of ANTXR2 (anthrax toxin receptor 2) are strongly correlated with anthrax toxin susceptibility. A recent genome-wide association study or GWAS identified that anthrax roxin receptor 2 (ANTXR2) was one of the risk loci for ankylosing spondylitis (AS). Previous study also showed that ANTXR2 could potentially affect new bone formation. This study aimed to investigate the possible mechanisms of ANTXR2 involved in AS pathogenesis.

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