14-3-3 eta/YWHAH Proteins, Antibodies, cDNA Clones Research Reagents

All 14-3-3 eta/YWHAH reagents are produced in house and quality controlled, including 4 14-3-3 eta/YWHAH Antibody, 45 14-3-3 eta/YWHAH Gene, 3 14-3-3 eta/YWHAH IP Kit, 1 14-3-3 eta/YWHAH Protein, 3 14-3-3 eta/YWHAH qPCR. All 14-3-3 eta/YWHAH reagents are ready to use.

14-3-3 eta/YWHAH Protein (1)

    14-3-3 eta/YWHAH Antibody (4)

      14-3-3 eta/YWHAH cDNA Clone (45)

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      14-3-3 eta/YWHAH Background

      YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on chromosome 22q12.3, a region which has been implicated by linkage studies in both BP and schizophrenia.

      14-3-3 eta/YWHAH References

      • Wakui H, et al. (1997) Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein. J Biol Chem. 272(13): 8153-6.
      • Toyooka K, et al. (2002) Isolation and structure of the mouse 14-3-3 eta chain gene and the distribution of 14-3-3 eta mRNA in the mouse brain. Brain Res Mol Brain Res. 100(1-2): 13-20.
      • Kim YS, et al. (2005) Role of 14-3-3 eta as a positive regulator of the glucocorticoid receptor transcriptional activation. Endocrinology. 146(7): 3133-40.
      • Grover D, et al. (2009) Family-based association of YWHAH in psychotic bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 150B(7): 977-83.

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