CASP2 Protein

CASP2 Protein Overview

CASP2 reagents

The CASP2 gene encodes caspase-2, which belongs to a family of proteases that mediate apoptosis. CASP2 is a developmentally regulated initiator caspase that poorly cleaves other caspases but can initiate permeabilization of the outer mitochondrial membrane, and that regulates diverse stress-induced signaling pathways (summary by Carlsson et al., 2011).

CASP2 protein family

Belongs to the peptidase C14A family.

CASP2 protein name

Recommended name
ICH1, MGC2181, PPP1R57, protein phosphatase 1, regulatory subunit 57

CASP2 Gene family protein

CASP2 Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 170-325 Caspase-2 subunit p18.

Molecular weight (Da)


Theoretical pI


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