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C1QA  Protein, Antibody, ELISA Kit, cDNA Clone

C1QA Related Area

C1QA Related Pathways

C1QA Related Protein, Antibody, cDNA Gene, and ELISA Kits

C1QA Related Protein, Antibody, cDNA Gene, and ELISA Kits

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C1QA Summary & Protein Information

C1QA Background

Subunit structure: C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
Subcellular location: Secreted.
Post-translational: O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups. {ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218}.
Involvement in disease: DISEASE: Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Note=The disease is caused by mutations affecting the gene represented in this entry.
Sequence similarity: Contains 1 C1q domain. {ECO:0000255|PROSITE-ProRule:PRU00368}.; Contains 1 collagen-like domain. {ECO:0000305}.
General information above from UniProt

C1QA Alternative Name

C1q,AI255395, [mus-musculus]

C1QA Related Studies

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