ZNF543 (Zinc Finger Protein 543, also known as DKFZp434H055) is located on human chromosome 19q13.43. The ZNF543 protein is ubiquitously expressed in ovary, thyroid and other tissues. Structurally, the encoded ZNF543 protein is reported to be 68404 Da in mass. 27 organisms have orthologs with human gene ZNF543. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. ZNF543 is related to nucleic acid binding. An important paralog of this gene is ZNF460. ZNF543 may be involved in transcriptional regulation.
- Abdelmohsen K, et al. (2009) Ubiquitin-mediated proteolysis of hur by heat shock. Embo j 28 (9): 1271-1282.