THAP domain-containing protein 6 (also known as THAP6 and MGC30052) is located on human chromosome 4q21.1. The THAP (Thanatos Associated Proteins) protein family in humans is implicated in various important cellular processes like epigenetic regulation, maintenance of pluripotency, transposition and disorders like cancers and hemophilia. The human THAP protein family which consists of twelve members of different lengths has a well-characterized amino terminal, zinc-coordinating, DNA-binding domain called the THAP domain.
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