Recombinant Anti-TROY Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-TROY Antibody, Rabbit Monoclonal General Information

Product name
Recombinant Anti-TROY Antibody, Rabbit Monoclonal
Validated applications
ELISA(Cap)
Species reactivity
Reacts with: Mouse
Specificity
Mouse TROY
Immunogen
Recombinant Mouse TNFRSF19 / TROY Protein (Catalog#50148-M08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNFRSF19 / TROY (rM TNFRSF19 / TROY; Catalog#50148-M08H; NP_001157627.1; Met1-Leu170).
Source
Monoclonal Rabbit IgG Clone #104
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-TROY Antibody, Rabbit Monoclonal Validated Applications

Notes
ELISA(Cap): This antibody will detect Mouse TNFRSF19 / TROY in ELISA pair set (Catalog: # SEK50148). In a sandwich ELISA, it can be used as capture antibody.
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-TROY Antibody, Rabbit Monoclonal: Synonyms

Anti-AL023044 Antibody; Anti-AW123854 Antibody; Anti-TAJ Antibody; Anti-TAJ-ALPHA Antibody; Anti-TRADE Antibody; Anti-Troy Antibody

TROY Background Information

Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
Full Name
tumor necrosis factor receptor superfamily, member 19
References
  • Hu S, et al. (1999) Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily. Genomics. 62(1): 103-7.
  • Qiu W, et al. (2010) Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP. J Biol Chem. 285(19): 14438-49.
  • Hisaoka T, et al. (2006) Characterization of TROY/TNFRSF19/TAJ-expressing cells in the adult mouse forebrain. Brain Res. 1110(1): 81-94.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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