Anti-LYPD3 Antibody, Rabbit Polyclonal General Information
Anti-LYPD3 Antibody, Rabbit Polyclonal
Reacts with: Mouse
Recombinant Mouse C4.4A / LYPD3 protein (Catalog#50546-M08H)
Produced in rabbits immunized with purified, recombinant Mouse C4.4A / LYPD3 (rM C4.4A / LYPD3; Catalog#50546-M08H; NP_598504.1; Met 1-His 287). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-LYPD3 Antibody, Rabbit Polyclonal: Synonyms
Anti-2310061G07Rik Antibody; Anti-C4.4a Antibody
LYPD3 Background Information
Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression
LY6/PLAUR domain containing 3
Smith B.A., et al., 2001, Cancer Res. 61:1678-85.
Wuerfel J., et al., 2001, Gene 262:35-41.
Clark H.F., et al., 2003, Genome Res. 13:2265-70.
Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-85.
Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-57.
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