Anti-Factor IX Antibody, Rabbit Polyclonal
Cat: 50362-T16
Cat: 50362-T16
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Anti-Factor IX Antibody, Rabbit Polyclonal General Information
Product name
Anti-Factor IX Antibody, Rabbit Polyclonal
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse Factor IX
Immunogen
Recombinant Mouse Coagulation Factor IX / FIX / F9 protein (Catalog#50362-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse Coagulation Factor IX / FIX / F9 (Catalog#50362-M08H; P16294; Met1-Thr471). Coagulation Factor IX / FIX / F9 specific IgG was purified by Mouse Coagulation Factor IX / FIX / F9 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-Factor IX Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| ELISA | 1:5000-1:10000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-Factor IX Antibody, Rabbit Polyclonal: Synonyms
Anti-AW111646 Antibody; Anti-Cf-9 Antibody; Anti-Cf9 Antibody
Factor IX Background Information
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.
Full Name
coagulation factor IX
References
- Onay U.V., et al., 2003, Br. J. Haematol. 120:656-659.
- Vidal F., et al., 2000, Br. J. Haematol. 111:549-551.
- Simioni P., et al., 2009, N. Engl. J. Med. 361:1671-1675.
- Espinos C., et al., 2009, Haematologica 88:235-236.
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