Recombinant Anti-TIM-1/KIM-1 Antibody, Rabbit Monoclonal

RRID Number: AB_2860287
EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-TIM-1/KIM-1 Antibody, Rabbit Monoclonal (Rabbit Monoclonal antibody) General Information

Product name
Recombinant Anti-TIM-1/KIM-1 Antibody, Rabbit Monoclonal
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human TIM-1/KIM-1
No cross-reactivity in ELISA with
Mouse KIM1
Human TIMD3
Rat KIM1
Immunogen
Recombinant Human KIM-1 / TIM1 / HACVR1 protein (Catalog#11051-H07H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human KIM-1 / TIM1 / HACVR1 (rh KIM-1 / TIM1 / HACVR1; Catalog#11051-H07H; AAC39862.1; Ser21-Gly290).
Source
Monoclonal Rabbit IgG Clone #n208
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-TIM-1/KIM-1 Antibody, Rabbit Monoclonal (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-TIM-1/KIM-1 Antibody, Rabbit Monoclonal: Synonyms

Anti-CD365 Antibody; Anti-HACVR Antibody; Anti-HAVCR Antibody; Anti-HAVCR-1 Antibody; Anti-KIM-1 Antibody; Anti-KIM1 Antibody; Anti-TIM Antibody; Anti-TIM-1 Antibody; Anti-TIM1 Antibody; Anti-TIMD-1 Antibody; Anti-TIMD1 Antibody

TIM-1/KIM-1 Background Information

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Full Name
hepatitis A virus cellular receptor 1
References
  • Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
  • Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
  • Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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