Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
1/1
Price:
Size:
Number:

Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal General Information

Product name
Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human PDGFRB
Immunogen
Recombinant Human PDGFRB / CD140b Protein (Catalog#10514-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human PDGFRB / CD140b (rh PDGFRB / CD140b; Catalog#10514-H08H; NP_002600.1; Met1-Lys531).
Source
Monoclonal Rabbit IgG Clone #206
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal Validated Applications

Application Dilution
FCM 1:25-1:100
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal Images

Flow cytometric analysis of Human PDGFRβ (CD140b) expression on MG63 cells. Cells were stained with purified anti-Human PDGFRβ (CD140b), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

Recombinant Anti-PDGFRB Antibody, Rabbit Monoclonal: Synonyms

Anti-CD140B Antibody; Anti-IBGC4 Antibody; Anti-IMF1 Antibody; Anti-JTK12 Antibody; Anti-KOGS Antibody; Anti-PDGFR Antibody; Anti-PDGFR-1 Antibody; Anti-PDGFR1 Antibody; Anti-PENTT Antibody

PDGFRB Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.
Full Name
platelet-derived growth factor receptor, beta polypeptide
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Suzuki S, et al. (2010) Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression, PDGF receptor- phosphorylation, and microvessel density in gastric cancer. BMC cancer. 10: 659.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait U.S.A.