Anti-LOK Antibody, Rabbit Polyclonal


Anti-LOK Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-LOK Antibody, Rabbit Polyclonal
Validated applications
Species reactivity
Reacts with: Human
Human LOK
Recombinant Human STK10 / LOK protein (Catalog#11724-H07E)
Produced in rabbits immunized with purified, recombinant Human STK10 / LOK (rh STK10 / LOK; Catalog#11724-H07E; NP_005981.3; Arg 18-Glu 317). STK10 / LOK specific IgG was purified by Human STK10 / LOK affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-LOK Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-LOK Antibody, Rabbit Polyclonal: Synonyms

Anti-LOK Antibody; Anti-PRO2729 Antibody

LOK Background Information

Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, which belongs to theprotein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells. The Ste2 family of serine/threonine kinases plays an important role in numerous cellular functions such as growth, apoptosis, and morphogenesis. STK1 is similar to several known polo-like kinase kinases. It can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. STK1 can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. Stk1 can associate with Plk1 in cells and furthermore can phosphorylate Plk1. It can also act on substrates such as myelin basic protein and histone 2A on serine and threonine residues.
Full Name
serine/threonine kinase 10
  • Kuramochi S, et al., 1997, J. Biol. Chem. 272 (36): 22679-84.
  • Kuramochi S, et al., 1999, Immunogenetics. 49 (5): 369-75. 
  • Walter, SA. et al., J Biol Chem 2003, 278 (20):18221-8.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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