Recombinant Human TRAILR3/TNFRSF10C Protein (Catalog#10415-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAILR3/TNFRSF10C (rh TRAILR3/TNFRSF10C; Catalog#10415-H08H; NP_003832.2; Met1-Pro235) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Monoclonal Rabbit IgG Clone #003
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
5 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human TNFRSF10C(CD263). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
tumor necrosis factor receptor superfamily member 10c
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