Recombinant Anti-DcR1/TRAILR3 Antibody (FITC), Rabbit Monoclonal

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Recombinant Anti-DcR1/TRAILR3 Antibody (FITC), Rabbit Monoclonal General Information

Product name
Recombinant Anti-DcR1/TRAILR3 Antibody (FITC), Rabbit Monoclonal
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human DcR1/TRAILR3
Immunogen
Recombinant Human TRAILR3/TNFRSF10C Protein (Catalog#10415-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAILR3/TNFRSF10C (rh TRAILR3/TNFRSF10C; Catalog#10415-H08H; NP_003832.2; Met1-Pro235) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Source
Monoclonal Rabbit IgG Clone #003
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
FITC
Concentration
5 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Recombinant Anti-DcR1/TRAILR3 Antibody (FITC), Rabbit Monoclonal Images

Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human TNFRSF10C(CD263). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.

Recombinant Anti-DcR1/TRAILR3 Antibody (FITC), Rabbit Monoclonal: Synonyms

Anti-CD263 Antibody; Anti-DCR1 Antibody; Anti-DCR1-TNFR Antibody; Anti-LIT Antibody; Anti-TRAIL-R3 Antibody; Anti-TRAILR3 Antibody; Anti-TRID Antibody

DcR1/TRAILR3 Background Information

TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
Full Name
tumor necrosis factor receptor superfamily member 10c
Related Pathways
  • Death Receptor Signaling
    Death Receptor Signaling

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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