Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal

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Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal General Information

Product name
Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human DcR1/TRAILR3
Immunogen
E. coli-derived Human DcR1 / TRAILR3 fragment
Preparation
Produced in rabbits immunized with E. coli-derived Human DcR1 / TRAILR3 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal Validated Applications

Application Dilution
WB 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal Images

Anti-DcR1/TRAILR3 rabbit polyclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size:65 kDa

Observed band size:70 kDa

(We are unsure as to the identity of these extra bands.)

Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal: Synonyms

Anti-CD263 Antibody; Anti-DCR1 Antibody; Anti-DCR1-TNFR Antibody; Anti-LIT Antibody; Anti-TRAIL-R3 Antibody; Anti-TRAILR3 Antibody; Anti-TRID Antibody

DcR1/TRAILR3 Background Information

TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
Full Name
tumor necrosis factor receptor superfamily member 10c
Related Pathways
  • Death Receptor Signaling
    Death Receptor Signaling

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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