Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal General Information
Anti-DcR1/TRAILR3 Antibody, Rabbit Polyclonal
Reacts with: Human
Recombinant Human DcR1/TNFRSF10C Protein (Catalog#10415-H08H)
Produced in rabbits immunized with purified, recombinant Human DcR1/TNFRSF10C (rh DcR1/TNFRSF10C; Catalog#10415-H08H; NP_003832.2; Met1-Pro235). DcR1/TNFRSF10C specific IgG was purified by Human DcR1/TNFRSF10C affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
PBS, pH7.0 with 0.03% Proclin300
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
tumor necrosis factor receptor superfamily member 10c
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