SIRT4 (Protein | Antibody | cDNA Clone | ELISA Kit)

All SIRT4 reagents are produced in house and quality controlled, including 1 SIRT4 Antibody, 17 SIRT4 Gene, 1 SIRT4 IP Kit, 1 SIRT4 qPCR. All SIRT4 reagents are ready to use.

SIRT4 Background

Downregulation of SIRT4 significantly increased tumor proliferation, migration and invasion. Additionally, downregulation of SIRT4 decreased the chemosensitivity of CRC cells by inhibiting cell apoptosis. Thus, these results suggest that SIRT4 may be a promising therapeutic target in CRC. SIRT4 in the control of energy metabolism and meiotic apparatus during oocyte maturation and indicate that SIRT4 is an essential factor determining oocyte quality. SIRT4 ameliorates MI-R injury through regulating mitochondrial function and apoptosis, and suggest that manipulating SIRT4 may be of clinical benefit in MI-R injury.