PIG3 (Protein | Antibody | cDNA Clone | ELISA Kit)

All PIG3 reagents are produced in house and quality controlled, including 3 PIG3 Antibody, 16 PIG3 Gene, 1 PIG3 IP Kit, 1 PIG3 Protein, 1 PIG3 qPCR. All PIG3 reagents are ready to use.

PIG3 Background

Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3.