HIPK2 (Protein | Antibody | cDNA Clone | ELISA Kit)

All HIPK2 reagents are produced in house and quality controlled, including 2 HIPK2 Antibody, 15 HIPK2 Gene, 1 HIPK2 qPCR. All HIPK2 reagents are ready to use.

More Product Popular With Customers

HIPK2 Background

There is a regulated interaction between the serine/threonine kinase HIPK2 and the ubiquitin E3 ligase Siah2 as a mechanism controlling the hypoxic response. HIPK2 has an important role as a negative regulator of gene expression, its elimination from promoter-associated repressor complexes allows the induction of a substantial fraction of hypoxia-induced genes. The tumour suppressor HIPK2 is an important regulator of cell death induced by DNA damage,