Galectin 3 / LGALS3 (Protein | Antibody | cDNA Clone | ELISA Kit)

All Galectin 3 / LGALS3 reagents are produced in house and quality controlled, including 8 Galectin 3 / LGALS3 Antibody, 1 Galectin 3 / LGALS3 ELISA, 60 Galectin 3 / LGALS3 Gene, 5 Galectin 3 / LGALS3 IP Kit, 1 Galectin 3 / LGALS3 Protein, 3 Galectin 3 / LGALS3 qPCR. All Galectin 3 / LGALS3 reagents are ready to use.

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Galectin 3 / LGALS3 Background

LGALS3, a member of the lectin family, has an important role in tumor progression through inhibition of apoptosis.The galectin-3 gene (LGALS3) encodes a beta-galactose binding lectin. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Galectin-3 is a beta-galactoside-binding lectin which is involved in modulating inflammation and apoptosis. Elevated expression of galectin-3 has been demonstrated in synovium of rheumatoid arthritis (RA).

Galectin 3 / LGALS3 References

  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.