G protein alpha S / GNAS (Protein | Antibody | cDNA Clone | ELISA Kit)

All G protein alpha S / GNAS reagents are produced in house and quality controlled, including 1 G protein alpha S / GNAS Antibody, 29 G protein alpha S / GNAS Gene, 1 G protein alpha S / GNAS IP Kit, 2 G protein alpha S / GNAS qPCR. All G protein alpha S / GNAS reagents are ready to use.

G protein alpha S / GNAS Antibody (1)

    G protein alpha S / GNAS cDNA Clone (29)

    NM_080426.3

    In expression vector

    NM_201616.1
    NM_001159656.1

    In cloning vector

    In lentiviral vector

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    G protein alpha S / GNAS Background

    G protein alphas (GNAS) mediates receptor-stimulated cAMP signalling, which integrates diverse environmental cues with intracellular responses. GNAS is a complex imprinted gene encoding the alpha-subunit of the stimulatory heterotrimeric G protein (Gsalpha). Inactivating mutations in Gsalpha-coding GNAS exons are responsible for Albright's hereditary osteodystrophy (AHO), which refers to a constellation of physical and developmental disorders including obesity, short stature, brachydactyly, cognitive impairment, and heterotopic ossification. GNAS mutations have been described in mucinous and non-mucinous epithelial neoplasms of the appendix, pancreas, and colon, with hotspot GNAS mutations found in up to two-thirds of pancreatic intraductal papillary mucinous neoplasms.