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A transferase/B transferase  ELISA Products

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    A transferase/B transferase Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    A transferase/B transferase Summary & Protein Information

    A transferase/B transferase Background

    Catalytic activity: UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.; UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
    Cofactor: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:17259183}; ; Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000269|PubMed:17259183};
    Domain: The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
    Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
    Post-translational: The soluble form derives from the membrane form by proteolytic processing.
    Sequence similarity: Belongs to the glycosyltransferase 6 family. {ECO:0000305}.
    General information above from UniProt

    A transferase/B transferase Alternative Name

    GTB,NAGAT,A3GALNT,A3GALT1, [homo-sapiens]
    NAGAT, [mus-musculus]

    A transferase/B transferase Related Studies

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