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ABHD4  ELISA Pair Set

All ABHD4 Reagents

ABHD4

ABHD4 ELISA Pair Set

ABHD4 Related Area

ABHD4 Related Pathways

    ABHD4 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    ABHD4 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    ABHD4 Summary & Protein Information

    ABHD4 Background

    Sequence similarity: Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. {ECO:0000305}.
    General information above from UniProt

    Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipase B that selectively hydrolyzes N-acyl phosphatidylethanolamines (NAPEs) and lysoNAPEs. ABH4 accepts lysoNAPEs bearing both saturated and polyunsaturated N-acyl chains as substrates and displays a distribution that closely mirrors lysoNAPE-lipase activity in mouse tissues. The existence of an NAPE-PLD-independent route for NAE biosynthesis and suggest that ABH4 plays a role in this metabolic pathway by acting as a (lyso)NAPE-selective lipase.

    ABHD4 Alternative Name

    ABH4, [homo-sapiens]
    ABH4,ABHD4,FLJ12816, [human]
    1110035H23Rik,Abh4,ABHD4,AI429574, [mouse]
    Abh4,AI429574,1110035H23Rik, [mus-musculus]

    ABHD4 Related Studies

  • Li F, et al. (2009) An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines. Mol Biol Rep. 36(4): 691-6.
  • Simon G.M, et al. (2006) Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta hydrolase 4 in this pathway. J. Biol. Chem. 281: 26465-72.
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