TRIB3 cDNA Clone: Expression and Clone Vector / Plasmid

TRIB3 cDNA / Gene Overview

TRIB3 gene / cDNA is a protein-coding gene which located on 20p13. The TRIB3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and zebrafish.128 organisms have orthologs with human gene TRIB3.

TRIB3 cDNA / Gene Function

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

TRIB3 cDNA / Gene Sequence

LOCUS NM_021158 2554 bp mRNA linear PRI 29-JUL-2018
Homo sapiens tribbles pseudokinase 3 (TRIB3), transcript variant 1, mRNA.

This sequence information is just for reference only.

TRIB3 cDNA / Gene Alias

  • dJ1103G7.3
  • TRB3

TRIB3 cDNA / Gene Expression

Broad expression in thyroid (RPKM 19.9), liver (RPKM 5.0) and 16 other tissues