TRIB3 cDNA Clone: Expression and Clone Vector / Plasmid
TRIB3 cDNA / Gene Overview
TRIB3 gene / cDNA is a protein-coding gene which located on 20p13. The TRIB3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and zebrafish.128 organisms have orthologs with human gene TRIB3.
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
TRIB3 cDNA / Gene Sequence
LOCUS NM_021158 2554 bp mRNA linear PRI 29-JUL-2018
Homo sapiens tribbles pseudokinase 3 (TRIB3), transcript variant 1, mRNA.
This sequence information is just for reference only.
TRIB3 cDNA / Gene Alias
TRIB3 cDNA / Gene Expression
Broad expression in thyroid (RPKM 19.9), liver (RPKM 5.0) and 16 other tissues
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