Transferrin Receptor / TFRC cDNA Clone: Expression and Clone Vector / Plasmid

Transferrin Receptor / TFRC cDNA / Gene Overview

TFRC gene / cDNA is a protein-coding gene which located on 3q29. The TFRC gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.213 organisms have orthologs with human gene TFRC.

Transferrin Receptor / TFRC cDNA / Gene Function

This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

Transferrin Receptor / TFRC cDNA / Gene Sequence

LOCUS
LOCUS NM_001128148 5093 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens transferrin receptor (TFRC), transcript variant 2, mRNA.
ACCESSION
NM_001128148
VERSION
NM_001128148.2

This sequence information is just for reference only.

Transferrin Receptor / TFRC Family & Reagents

Gene family

Transferrin Receptor / TFRC Gene family reagents (CD molecules)

Approved Symbol Reagent list
LAMP3
CD302
ICOS
KLRC1
TNFSF8
ENTPD1
PDGFRB
TNFSF11
BTN3A1
GYPA
Approved Symbol Reagent list
CD244
IL10RB
LILRB2
CLEC10A
TSPAN7
FCRL1
NRP1
CRTAM
CD79A
CD48

Transferrin Receptor / TFRC cDNA / Gene Alias

  • CD71
  • p90
  • TFR1

Transferrin Receptor / TFRC cDNA / Gene Expression

Broad expression in bone marrow (RPKM 101.5), placenta (RPKM 60.5) and 23 other tissues

Recombinant Transferrin Receptor / TFRC protein citations

Title
Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells
Year
2014
Author
Perkins, TN;Peeters, PM;Shukla, A;Arijs, I;Dragon, J;Wouters, EF;Reynaert, NL;Mossman, BT;
Journal
Hum. Mol. Genet.