Stem Cell Receptor

Stem cells are mother cells that have the unique ability to develop into any type of cell in the body. One of the main characteristics of stem cells is their ability to self-renew or multiply while maintaining the potential to develop into other types of cells. Stem cells can become cells of the blood, heart, bones, skin, muscles and brain, etc. There are different sources of stem cells but all types of stem cells have the same capacity to develop into multiple types of cells.

A range of receptors can be expressed on stem cells. Tie2 is expressed on fetal liver hematopoietic stem cells (HSCs). KIT is a cell-surface receptor expressed on mast/stem cells and plays important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. Mesenchymal stem cells (MSCs) are adult stem cells, which reside in the bone marrow and other mesenchymal tissues. However, MSCs express a large number of cell surface receptors associated with their function, including: growth factor receptors, chemokine receptors, cytokine receptors and phenotypic receptor.

Stem Cell Receptors

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IL2RA/IL-2RA/CD25 CD45/PTPRC TFRC/CD71
G-CSFR/CD114/CSF3R CD116/GM-CSFR IL3RA/CD123
IL6R/IL-6R/CD126 IL7R/IL-7R/CD127 FLT3/CD135/FLK-2
PDGFRA/CD140a PDGFRB/CD140b DDR1/MCK10/CD167
SIRPA/SIRP alpha/CD172a SIRPB1 CXCR3
CXCR4/CD184 CCR3/CD193 CCR5
IGF1R/CD221/IGF-I R NGFR/P75 TLR1 / CD281
TLR2 (CD282) TLR4 / TLR-4 VEGFR2/KDR/Flk-1/CD309
F11R/CD321 FGFR4/CD334 HER2/ERBB2
Frizzled-9/FZD9 C3AR1 ERBB3/HER3
EphA2/Eph Receptor A2 GPR19 GPR56
ROR1/NTRKR1 TRIM28 VEGFR3/FLT-4
TRA2A TRA2B Tie2/CD202b/TEK
KIT / c-KIT / CD117    
Receptors
Receptors Classification
Receptors by Differentiation Cells
B Cell Receptor
Dendritic Cell Receptor
Granulocyte Receptor
Monocyte Receptor
NK Cell Receptor
Stem Cell Receptor
T Cell Receptor
Receptors by Functions
Receptors Reagent Products
Receptors by Species