PMP2: PMP2 Protein | PMP2 Antibody

PMP2 Gene family

PMP2 Background

Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells of the central and peripheral nervous systems, the oligodendrocytes and Schwann cells, respectively. PMP2 may play a role in lipid transport protein in Schwann cells. It forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

Reference for PMP2

  • Hayasaka, K. et al., 1993, Genomics. 18(2): 244-8.
  • Polverini, E. et al., 2006, J Struct Biol. 153(3): 253-63.
  • Gould,R.M.et al., 2008, Neuron Glia Biol. 4(2):137-52.

PMP2 Protein

PMP2 protein function

May play a role in lipid transport protein in Schwann cells. May bind cholesterol. {ECO:0000269|PubMed:20421974}.

PMP2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    132.00
  • Mass (Da)
    14.00

PMP2 Antibody

There are 4 PMP2 antibodies which are validated in multiple tissues with various applications, including ELISA. There are 4 PMP2 antibody for ELISA. Among all these PMP2 antibodies, there are 1 anti-PMP2 mouse monoclonal antibodies , 1 anti-PMP2 rabbit monoclonal antibodies , 2 anti-PMP2 rabbit polyclonal antibodies . All the PMP2 anbodies are produced in house and all are in stock. PMP2 antibody customerized service is available.

PMP2 Gene

PMP2 gene / cDNA is a protein-coding gene which located on 8q21.13. The PMP2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and C.elegans.62 organisms have orthologs with human gene PMP2.