CXCR4/CD184 cDNA Clone: Expression and Clone Vector / Plasmid
CXCR4/CD184 cDNA / Gene Overview
CXCR4 cDNA / gene is a gene with protein product which located on 2q22.1. The CXCR4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 231 organisms have orthologs with human gene CXCR4.
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
CXCR4/CD184 cDNA / Gene Sequence
AF005058 5161 bp DNA linear PRI 21-SEP-2000
Homo sapiens chemokine receptor (CXCR-4) gene, complete cds.
This sequence information is just for reference only.
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