Antioxidant enzymes are capable of stabilizing, or deactivating free radicals before they attack cellular components. They act by reducing the energy of the free radicals or by giving up some of their electrons for its use, thereby causing it to become stable. In addition, Antioxidant enzymes may also interrupt with the oxidizing chain reaction to minimize the damage caused by free radicals. For the past decade, countless studies have been devoted to the beneficial effects of antioxidant enzymes.
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes. Because ROS/RNS can induce oxidative injury and act in redox signaling, enzymes metabolizing them will inherently promote either health or disease, depending on the physiological context. It is thus misleading to consider conventionally called antioxidant enzymes to be largely, if not exclusively, health protective. Antioxidant enzymes, such as the glutathione peroxidase family, protect cell surfaces, extracellular fluid components, and other enzymes from oxidative stress by catalyzing the reduction of hydrogen peroxide, lipid peroxides, and organic hydroperoxide using reduced glutathione.
Sino Biological offers a comprehensive set of tools for Antioxidant enzymes related studies, including recombinant proteins, antibodies (rabbit mAbs, mouse mAbs, rabbit pAbs), ELISA kits, and ORF cDNA clones.